The Vortex–Pattern–Resonance (VPR) model presents a unified conceptual and mathematical framework for understanding reality as a hierarchical system of forms governed by entropy, informational energy, and resonant interactions. Drawing from quantum mechanics, thermodynamics, biology, and cosmology, VPR posits that reality emerges from a quantum fog through symmetry breaking, with forms stabilizing across levels via local entropy reduction. The extension, VPR+, applies this to resonant phenomena in biological macromolecules (e.g., insulin stabilization) and astrophysical signals (e.g., fast radio bursts), introducing informational energy \( E_{\text{info}} \) as a measure of structural resilience. This interdisciplinary model bridges micro- and macro-scales, offering predictive tools for protein engineering and cosmic signal analysis. We propose experimental validations and discuss implications for philosophy of physics and applied sciences.

Modern physics and biology face unresolved anomalies—such as quantum non-locality, the emergence of life, and the persistence of complex systems against entropy—that classical models cannot fully explain. The VPR model, inspired by Einstein’s rejection of a purely probabilistic universe, reinterprets reality as a structured hierarchy of forms—stable configurations of energy and information—that emerge, interact, and evolve under entropic constraints. Unlike reductionist approaches, VPR emphasizes emergence, resonance, and the role of the observer in “fixing” reality.

The core VPR framework outlines a progression from undifferentiated potential to conscious systems. Its extension, VPR+, links informational energy to practical applications in biochemistry and astrophysics, providing a unified grammar for reality where entropy drives transformation, while resonance and information enable persistence.